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Key Publications

Submitted and Published Papers

Publications: Publications

Lee RH, Wu CY, Citadin CT, Couto E Silva A, Possoit HE, Clemons GA, Acosta HC, de la Llama VA, Neumann JT, Lin HW. Activation of Neuropeptide Y2 Receptor Can Inhibit Global Cerebral Ischemia-Induced Brain Injury. NeuroMolecular Medicine. 2021 May 21. doi: 10.1007/s12017-021-08665-z. PubMed PMID: 34019239.

Wu CY, Couto E Silva A, Citadin CT, Clemons GA, Acosta CH, Knox BA, Grames MS, Rodgers KM, Lee RH, Lin HW. Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction. Prostaglandins Leukot Essent Fatty Acids (PLEFA). 2021 Feb;165:102227. doi: 10.1016/j.plefa.2020.102227. Epub 2020 Dec 17. PMID: 33445063.

Lee RH (Corresponding author), Grames MS, Wu CY, Lien CF, Couto E Silva A, Possoit HE, Clemons GA, Citadin CT, Neumann JT, Pastore D, Lauro D, Della-Morte D, Lin HW. (2020) Upregulation of serum and glucocorticoid-regulated kinase 1 exacerbates brain injury and neurological deficits after cardiac arrest. Am J Physiol Heart Circ Physiol 2020 Nov 1;319(5):H1044-H1050. doi: 10.1152/ajpheart.00399.2020. Epub 2020 Sep 18. PMID: 32946263.

Chen P, Wu CY, Clemons GA, Citadin CT, Couto E Silva A, Possoit HE, Azizbayeva R, Forren NE, Liu C, Rao KN, Krzywanski DM, Lee RH, Neumann JT, Lin HW. (2020) Stearic acid methyl ester affords neuroprotection and improves functional outcomes after cardiac arrest. Prostaglandins, leukotrienes, and essential fatty acids (PLEFA).

Wu CY, Clemons GA, Lopz-Toledano MA, Citadin CT, Lee RH, Lin HW. (2020) SC411 enhances cerebral blood flow after ischemia in the Townes mouse model of sickle cell disease. Prostaglandins, leukotrienes, and essential fatty acids (PLEFA).

Couto E Silva A, Wu CY, Citadin CT, Clemons GA, Possoit HE, Grames MS, Lien CF, Minagar A, Lee RH, Frankel A, Lin HW. Protein Arginine Methyltransferases in Cardiovascular and Neuronal Function. Molecular Neurobiology. 2019 Dec 10. doi: 10.1007/s12035-019-01850-z. PMID:31823198.

Wu CY, Lee RH, Lee MH, Do Couto E Silva A, Hsieh TH, Possoit HE, Brackett AL, and Lin HW. (2018). Role of neuroinflammation in pathophysiology of traumatic brain injury. Neuroinflammation. Amsterdam, Netherlands, Elsevier.

Lee RH, Couto E Silva A, Possoit HE, Lerner FM, Azizbayeva R, Citadin CT, Wu CY, Neumann JT, Lin HW. (2018) Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest. Prostaglandins, leukotrienes, and essential fatty acids (PLEFA). Nov 23. pii: S0952-3278(18)30212-6. doi: 10.1016/j.plefa.2018.11.011. PMID: 30514597.

Lee RH, Lee MH, Wu CY, Couto E Silva A, Possoit HE, Hsieh TH, Minagar A, Lin HW. Cerebral ischemia and neuroregeneration. Neural Regen Res. 2018 Mar; 13(3): 373–385.  PMID: 29623912.

Wu CY, Lerner FM, Couto E Silva A, Possoit HE, Hsieh TH, Neumann JT, Minagar A, Lin HW, and Lee RH. (2018). Utilizing the modified T-maze to assess functional memory outcomes after cardiac arrest. J. Vis. Exp. (131), e56694, doi:10.3791/56694. PMID: 29364254. (Corresponding author).

Lee RH, Couto E Silva A, Lerner FM, Wilkins CS, Valido SE, Klein DD, Wu CY, Neumann JT, Della-Morte D, Koslow SH, Minagar A, and Lin HW. (2017) Interruption of Perivascular Sympathetic Nerves of Cerebral Arteries Offers Neuroprotection Against Ischemia. Am J Physiol Heart Circ Physiol 312(1): H182-188. PMID: 27864234.

Lee RH, Vasquez JJ, Do Couto E Silva A, Klein DD, Valido SE, Chen JA, Lerner FM, Wu CY, and Lin HW (2015). Fatty acid methyl esters as a potential therapy against cerebral ischemia. Oilseeds and fats, Crops and Lipids, DOI: 10.1051/ocl/2015040.

Wu CY, Lee RH, Chen PY, Tsai AP, Chen MF, Kuo JS, and Lee TJ. (2014). L-type calcium channels in sympathetic α3β2-nAChR-mediated cerebral nitrergic neurogenic vasodilation. Acta Physiol 211(4): 544-558. PMID: 24825168.

Lee RH, Wilkins CS, Do Couto E Silva A, Valido SE, Wu CY, and Lin HW. (2014). Fatty Acids in Vascular Health. Palmitic Acid: Occurrence, Biochemistry and Health Effects. Hauppauge NY. NOVA.

Lee RH, Tseng TY, Wu CY, Chen PY, Chen MF, Kuo JS, and Lee TJ. (2012). Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries. PLoS One 7(7): e40326. PMID: 22792283.

Chen MF, Huang YC, Long C, Yang HI, Lee RH, Chen PY, Hoffer BJ, and Lee TJ. (2012). Bimodal effects of fluoxetine on cerebral nitrergic neurogenic vasodilation in porcine large cerebral arteries. Neuropharmacology 62(4): 1651-1658. PMID: 22155207.

Lee TJ, Chang HH, Lee RH, Chen PY, Lee YC, Kuo JS, and Chen MF. (2011). Axo-axonal interaction in autonomic regulation of the cerebral circulation. Acta physiologica 203(1): 25-35. PMID: 21159131.

Lee RH, Liu YQ, Chen PY, Liu CH, Chen MF, Lin HW, Kuo JS, Premkumar LS, and Lee TJ. (2011). Sympathetic α3β2--nAChRs mediate cerebral neurogenic nitrergic vasodilation in the swine. Am J Physiol Heart Circ Physiol 301(2): H344-354. PMID: 21536845.

Lee RH, LEE CC, Lee RP, and Chen HI. (2005). Blood chemistry of nonstroke cerebral small vessel disease. Chinese Journal of Radiology 30(3): 159-166.

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